So I run perl from Macports because except for gentoo my experience with system perls has been ... poor. This tends to lead to fun when installing non-standard external libraries and the perl modules that love^Wwrap them.
Today was GD in which I found http://blog.joel.co.uk/index.php?itemid=299 invaluable.
I leave this as a pointer for others. Also a tip, when trying to install pdflib_lite ... it helps if you have a shared perl (libperl).