I have been following the podcasts related the 2600 magazine for some time now.
And I have grown rather fond of these characters, who week after week, discuss and debate everything from a hacker perspective.
I have tried with other podcasts (perlcast not included), even in danish, but none of these seem to make me go back.
Hak5 was quite entertaining, but after the summer break I never really got started again - all of the others I have tried out, have simply proved boring, too end-user, simply just rumormongering or news relaying...
So I stick to my beloved Off the (Hook|Wall) no matter how crazy those people seem and perlcast of course, since with those I am at least entertained and educated.
Recommendations for alternative podcasts are more than welcome.