A buddy that does telecom work and likes Perl was reluctantly forced to go to c#/vb for some web services type of stuff.
If i recall his problem was mostly that Perl doesn't have enough good hooks into COM stuff and mabye even .NET.
He looked in all the right places and posted questions put just heard chirping crickets.
As much as I don't want to learn Python I do find it's ... pervasiveness interesting, with things like IronPython and Jython.
I guess my only real lament for him is the lack of hooks into Microsoft's latest money pit.
That being said, one has to use the best tool for the job instead of pulling out the swiss army chainsaw all the time.
Maybe I should wish for better COM/.NET fu and lots of tuits instead of lamenting.