Last week, Fedora publised an update to perl, perl-5.10.0-27.fc9.i386. This update drops /usr/lib/perl5.10/site_lib from @INC. Since this is where earlier versions of perl preferred to install modules, you are either left with reinstalling all the modules again, or setting the PERL5LIB environment variable to add it back in.
Aside from that, and not installing CPAN by default, it was great for the whole two weeks that I got to use it.
WebGUI 7.5 seems to run fine on it.
I doubt there has been a single release of RH/Fedora in the history of that organization which did not somehow deliberately cripple Perl.
