Got home from New Years Eve party to find my computer acting odd and eventually totally locking up. Turns out I had ended up with a bad sector on one of my drives. Rebooted, the the drive was marked as failed. (But by that time the drive had figured out that it was a bad sector and to remap it.) Reactivated the drive, waited a while for it to re-sync, and all was back to normal. No data loss! (And only minor hassle.)